A Novel Stable Isotope Approach Demonstrates Surprising Degree of Age-Related Decline in Skeletal Muscle Collagen Proteostasis

Age-related deterioration in turnover of collagen proteins accelerates extracellular matrix fibrosis and hinders adaptation to external stimuli. This project sought to understand factors that increase skeletal muscle fibrosis with age by studying what we term the dynamic protein pool. We hypothesize...

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Detaylı Bibliyografya
Yayımlandı:Function (Oxf)
Asıl Yazarlar: Abbott, Claire B, Lawrence, Marcus M, Kobak, Kamil A, Lopes, Erika Barboza Prado, Peelor, Frederick F, Donald, Elizabeth J, Van Remmen, Holly, Griffin, Timothy M, Miller, Benjamin F
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2021
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8187230/
https://ncbi.nlm.nih.gov/pubmed/34124684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/function/zqab028
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