Adenosine/TGFβ axis in regulation of mammary fibroblast functions

Cancer associated fibroblasts (CAF) play a key role in cancer progression and metastasis. Diminished TGFβ response on CAF correlates with poor outcome and recurrence in cancer patients. Mechanisms behind lost TGFβ signaling on CAF are poorly understood, but, utilizing MMTV-PyMT mouse model, we have...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Vasiukov, Georgii, Menshikh, Anna, Owens, Philip, Novitskaya, Tatiana, Hurley, Paula, Blackwell, Timothy, Feoktistov, Igor, Novitskiy, Sergey V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8186761/
https://ncbi.nlm.nih.gov/pubmed/34101732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0252424
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