BMPR2 loss in fibroblasts promotes mammary carcinoma metastasis via increased inflammation

Bone Morphogenetic Protein (BMP) receptors mediate a diverse range of signals to regulate both development and disease. BMP activity has been linked to both tumor promoting and suppressive functions in both tumor cells and their surrounding microenvironment. We sought to investigate the requirement...

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發表在:Mol Oncol
Main Authors: Pickup, Michael W., Hover, Laura D., Polikowsky, Eleanor R., Chytil, Anna, Gorska, Agnieszka E., Novitskiy, Sergey V., Moses, Harold L., Owens, Philip
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2014
主題:
Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277920/
https://ncbi.nlm.nih.gov/pubmed/25205038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.08.004
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