BMPR2 loss in fibroblasts promotes mammary carcinoma metastasis via increased inflammation

Bone Morphogenetic Protein (BMP) receptors mediate a diverse range of signals to regulate both development and disease. BMP activity has been linked to both tumor promoting and suppressive functions in both tumor cells and their surrounding microenvironment. We sought to investigate the requirement...

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Détails bibliographiques
Publié dans:Mol Oncol
Auteurs principaux: Pickup, Michael W., Hover, Laura D., Polikowsky, Eleanor R., Chytil, Anna, Gorska, Agnieszka E., Novitskiy, Sergey V., Moses, Harold L., Owens, Philip
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2014
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277920/
https://ncbi.nlm.nih.gov/pubmed/25205038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.08.004
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