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BMPR2 loss in fibroblasts promotes mammary carcinoma metastasis via increased inflammation

Bone Morphogenetic Protein (BMP) receptors mediate a diverse range of signals to regulate both development and disease. BMP activity has been linked to both tumor promoting and suppressive functions in both tumor cells and their surrounding microenvironment. We sought to investigate the requirement...

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Bibliografske podrobnosti
izdano v:Mol Oncol
Main Authors: Pickup, Michael W., Hover, Laura D., Polikowsky, Eleanor R., Chytil, Anna, Gorska, Agnieszka E., Novitskiy, Sergey V., Moses, Harold L., Owens, Philip
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277920/
https://ncbi.nlm.nih.gov/pubmed/25205038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.08.004
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