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The role of SQSTM1 (p62) in mitochondrial function and clearance in human cortical neurons
Sequestosome-1 (SQSTM1/p62) is involved in cellular processes such as autophagy and metabolic reprogramming. Mutations resulting in the loss of function of SQSTM1 lead to neurodegenerative diseases including frontotemporal dementia. The pathogenic mechanism that contributes to SQSTM1-related neurode...
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| Publié dans: | Stem Cell Reports |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Elsevier
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8185463/ https://ncbi.nlm.nih.gov/pubmed/33891871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2021.03.030 |
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