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Enantioselective hydrogenation of annulated arenes: controlled formation of multiple stereocenters in adjacent rings
We report a method for the enantioselective hydrogenation of annulated arenes using 4H-pyrido[1,2-a]pyrimidinones as substrates. The method selectively generates multiple stereocenters in adjacent rings leading to architecturally complex motifs, which resemble bioactive molecules. The mechanistic st...
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| Publicado no: | Chem Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society of Chemistry
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8179591/ https://ncbi.nlm.nih.gov/pubmed/34163775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc07099h |
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