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Enantioselective synthesis of 2-oxazolidinones by ruthenium(ii)–NHC-catalysed asymmetric hydrogenation of 2-oxazolones
An efficient synthesis of optically active 4-substituted 2-oxazolidinones by the ruthenium(ii)–NHC-catalysed asymmetric hydrogenation of 2-oxazolones was developed. Excellent enantioselectivities (up to 96% ee) and yields (up to 99%) were obtained for a variety of substrates, bearing a range of func...
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| Gepubliceerd in: | Chem Sci |
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| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Royal Society of Chemistry
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6063072/ https://ncbi.nlm.nih.gov/pubmed/30090313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc01869c |
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