Rutaecarpine targets hERG channels and participates in regulating electrophysiological properties leading to ventricular arrhythmia

Drug‐mediated or medical condition‐mediated disruption of hERG function accounts for the main cause of acquired long‐QT syndrome (acLQTs), which predisposes affected individuals to ventricular arrhythmias (VA) and sudden death. Many Chinese herbal medicines, especially alkaloids, have risks of arrhy...

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Dettagli Bibliografici
Pubblicato in:J Cell Mol Med
Autori principali: Zhan, Ge, Wang, Fang, Ding, Yun‐qi, Li, Xiang‐hua, Li, Yue‐xin, Zhao, Zheng‐rong, Li, Jia‐xin, Liu, Yan, Zhao, Xin, Yan, Cai‐chuan, Li, Bao‐xin
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8178274/
https://ncbi.nlm.nih.gov/pubmed/33939251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16292
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