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Rutaecarpine targets hERG channels and participates in regulating electrophysiological properties leading to ventricular arrhythmia
Drug‐mediated or medical condition‐mediated disruption of hERG function accounts for the main cause of acquired long‐QT syndrome (acLQTs), which predisposes affected individuals to ventricular arrhythmias (VA) and sudden death. Many Chinese herbal medicines, especially alkaloids, have risks of arrhy...
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| Publicado no: | J Cell Mol Med |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8178274/ https://ncbi.nlm.nih.gov/pubmed/33939251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16292 |
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