Rutaecarpine targets hERG channels and participates in regulating electrophysiological properties leading to ventricular arrhythmia

Drug‐mediated or medical condition‐mediated disruption of hERG function accounts for the main cause of acquired long‐QT syndrome (acLQTs), which predisposes affected individuals to ventricular arrhythmias (VA) and sudden death. Many Chinese herbal medicines, especially alkaloids, have risks of arrhy...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Zhan, Ge, Wang, Fang, Ding, Yun‐qi, Li, Xiang‐hua, Li, Yue‐xin, Zhao, Zheng‐rong, Li, Jia‐xin, Liu, Yan, Zhao, Xin, Yan, Cai‐chuan, Li, Bao‐xin
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8178274/
https://ncbi.nlm.nih.gov/pubmed/33939251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16292
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