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Sustained and targeted delivery of siRNA/DP7‐C nanoparticles from injectable thermosensitive hydrogel for hepatocellular carcinoma therapy

Hepatocellular carcinoma (HCC) is one of the most lethal cancers in humans. The inhibition of peptidyl‐prolyl cis/trans isomerase (Pin1) gene expression may have great potential in the treatment of HCC. N‐Acetylgalactosamine (GalNAc) was used to target the liver. Cholesterol‐modified antimicrobial p...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Zhao, Binyan, Zhou, Bailing, Shi, Kun, Zhang, Rui, Dong, Chunyan, Xie, Daoyuan, Tang, Lin, Tian, Yaomei, Qian, Zhiyong, Yang, Li
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8177784/
https://ncbi.nlm.nih.gov/pubmed/33792132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14903
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