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Injectable and protease-degradable hydrogel for siRNA sequestration and triggered delivery to the heart
Injectable hydrogels have significant therapeutic potential for treatment of myocardial infarction (MI) through tissue bulking and local drug delivery, particularly for small interfering RNAs (siRNAs). As siRNA targets are identified as potential treatments for MI, hydrogels may bolster efficacy thr...
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| Pubblicato in: | J Control Release |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6134398/ https://ncbi.nlm.nih.gov/pubmed/29981357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.07.004 |
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