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27-plex Tandem Mass Tag Mass Spectrometry for Profiling Brain Proteome in Alzheimer's Disease

Multiplexed isobaric labeling methods, such as Tandem Mass Tags (TMT), remarkably improve the throughput of quantitative mass spectrometry. Here we present a 27-plex TMT method coupled with two-dimensional liquid chromatography (LC/LC) for extensive peptide fractionation and high-resolution tandem m...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Anal Chem
Päätekijät: Wang, Zhen, Yu, Kaiwen, Tan, Haiyan, Wu, Zhiping, Cho, Ji-Hoon, Han, Xian, Sun, Huan, Beach, Thomas G., Peng, Junmin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8176402/
https://ncbi.nlm.nih.gov/pubmed/32343560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.0c00655
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