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27-plex Tandem Mass Tag Mass Spectrometry for Profiling Brain Proteome in Alzheimer's Disease
Multiplexed isobaric labeling methods, such as Tandem Mass Tags (TMT), remarkably improve the throughput of quantitative mass spectrometry. Here we present a 27-plex TMT method coupled with two-dimensional liquid chromatography (LC/LC) for extensive peptide fractionation and high-resolution tandem m...
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| Publicado no: | Anal Chem |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8176402/ https://ncbi.nlm.nih.gov/pubmed/32343560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.0c00655 |
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