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Roles of WNK4 and SPAK in K(+)-mediated dephosphorylation of the NaCl cotransporter
Phosphorylation of the thiazide-sensitive NaCl cotransporter (NCC) in the distal convoluted tubule (DCT) is altered rapidly in response to changes in extracellular K(+) concentration ([K(+)]). High extracellular [K(+)] is believed to activate specific phosphatases to dephosphorylate NCC, thereby red...
Enregistré dans:
| Publié dans: | Am J Physiol Renal Physiol |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8174808/ https://ncbi.nlm.nih.gov/pubmed/33719576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00459.2020 |
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