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Mechanisms of WNK1 and WNK4 interaction in the regulation of thiazide-sensitive NaCl cotransport

With-no-lysine (WNK) kinases are highly expressed along the mammalian distal nephron. Mutations in either WNK1 or WNK4 cause familial hyperkalemic hypertension (FHHt), suggesting that the protein products converge on a final common pathway. We showed previously that WNK4 downregulates thiazide-sensi...

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書誌詳細
主要な著者: Yang, Chao-Ling, Zhu, Xiaoman, Wang, Zhaohong, Subramanya, Arohan R., Ellison, David H.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1074678/
https://ncbi.nlm.nih.gov/pubmed/15841204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200522452
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