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The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex
The pathogenesis of essential hypertension remains unknown, but thiazide diuretics are frequently recommended as first-line treatment. Recently, familial hyperkalemic hypertension (FHHt) was shown to result from activation of the thiazide-sensitive Na-Cl cotransporter (NCC) by mutations in WNK4, alt...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2045602/ https://ncbi.nlm.nih.gov/pubmed/17975670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32033 |
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