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Regulation of the renal NaCl cotransporter by the WNK/SPAK pathway: lessons learned from genetically altered animals

The renal thiazide-sensitive NaCl cotransporter (NCC) is the major salt transport pathway in the distal convoluted tubule of the mammalian nephron. NCC activity is critical for modulation of arterial blood pressure and serum potassium levels. Reduced activity of NCC in genetic diseases results in ar...

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Bibliografski detalji
Izdano u:Am J Physiol Renal Physiol
Glavni autori: Ostrosky-Frid, Mauricio, Castañeda-Bueno, María, Gamba, Gerardo
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6383199/
https://ncbi.nlm.nih.gov/pubmed/30089030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00288.2018
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