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Regulation of the renal NaCl cotransporter by the WNK/SPAK pathway: lessons learned from genetically altered animals

The renal thiazide-sensitive NaCl cotransporter (NCC) is the major salt transport pathway in the distal convoluted tubule of the mammalian nephron. NCC activity is critical for modulation of arterial blood pressure and serum potassium levels. Reduced activity of NCC in genetic diseases results in ar...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Am J Physiol Renal Physiol
मुख्य लेखकों: Ostrosky-Frid, Mauricio, Castañeda-Bueno, María, Gamba, Gerardo
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Physiological Society 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6383199/
https://ncbi.nlm.nih.gov/pubmed/30089030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00288.2018
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