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Regulation of the renal NaCl cotransporter by the WNK/SPAK pathway: lessons learned from genetically altered animals
The renal thiazide-sensitive NaCl cotransporter (NCC) is the major salt transport pathway in the distal convoluted tubule of the mammalian nephron. NCC activity is critical for modulation of arterial blood pressure and serum potassium levels. Reduced activity of NCC in genetic diseases results in ar...
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| Publicado no: | Am J Physiol Renal Physiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6383199/ https://ncbi.nlm.nih.gov/pubmed/30089030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00288.2018 |
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