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Adapting isotonic dose-finding to a dynamic set of drug combinations with application to a phase I leukemia trial

BACKGROUND/AIMS: This paper describes the proposed design of a Phase I study evaluating the safety of ceramide nanoliposome and vinblastine among an initial set of nineteen possible dose combinations in patients with relapsed/refractory acute myeloid leukemia and patients with untreated acute myeloi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Clin Trials
Egile Nagusiak: Wages, Nolan A, Reed, Daniel R, Keng, Michael K, Conaway, Mark R, Petroni, Gina R
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172388/
https://ncbi.nlm.nih.gov/pubmed/33426919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774520983484
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