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A Phase I/II adaptive design to determine the optimal treatment regimen from a set of combination immunotherapies in high-risk melanoma
In oncology, vaccine-based immunotherapy often investigates regimens that demonstrate minimal toxicity overall and higher doses may not correlate with greater immune response. Rather than determining the maximum tolerated dose, the goal of the study becomes locating the optimal biological dose, whic...
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| Publicado no: | Contemp Clin Trials |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4380742/ https://ncbi.nlm.nih.gov/pubmed/25638752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cct.2015.01.016 |
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