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Adapting isotonic dose-finding to a dynamic set of drug combinations with application to a phase I leukemia trial
BACKGROUND/AIMS: This paper describes the proposed design of a Phase I study evaluating the safety of ceramide nanoliposome and vinblastine among an initial set of nineteen possible dose combinations in patients with relapsed/refractory acute myeloid leukemia and patients with untreated acute myeloi...
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| Publicado no: | Clin Trials |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8172388/ https://ncbi.nlm.nih.gov/pubmed/33426919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774520983484 |
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