Carboxylesterase Notum Is a Druggable Target to Modulate Wnt Signaling

[Image: see text] Regulation of the Wnt signaling pathway is critically important for a number of cellular processes in both development and adult mammalian biology. This Perspective will provide a summary of current and emerging therapeutic opportunities in modulating Wnt signaling, especially thro...

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Veröffentlicht in:J Med Chem
Hauptverfasser: Bayle, Elliott D., Svensson, Fredrik, Atkinson, Benjamin N., Steadman, David, Willis, Nicky J., Woodward, Hannah L., Whiting, Paul, Vincent, Jean-Paul, Fish, Paul V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2021
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172013/
https://ncbi.nlm.nih.gov/pubmed/33783220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.0c01974
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