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Small-molecule inhibitors of carboxylesterase Notum

Notum has recently been identified as a negative regulator of Wnt signaling through the removal of an essential palmitoleate group from Wnt proteins. There are emerging reports that Notum plays a role in human disease, with published data suggesting that targeting Notum could represent a new therape...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Future Med Chem
Asıl Yazarlar: Zhao, Yuguang, Jolly, Sarah, Benvegnu, Stefano, Jones, E Yvonne, Fish, Paul V
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Newlands Press Ltd 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8130783/
https://ncbi.nlm.nih.gov/pubmed/33882714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2021-0036
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