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Small-molecule inhibitors of carboxylesterase Notum
Notum has recently been identified as a negative regulator of Wnt signaling through the removal of an essential palmitoleate group from Wnt proteins. There are emerging reports that Notum plays a role in human disease, with published data suggesting that targeting Notum could represent a new therape...
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| Udgivet i: | Future Med Chem |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Newlands Press Ltd
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8130783/ https://ncbi.nlm.nih.gov/pubmed/33882714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2021-0036 |
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