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Flavin-dependent halogenases catalyze enantioselective olefin halocyclization

Halocyclization of alkenes is a powerful bond-forming tool in synthetic organic chemistry and a key step in natural product biosynthesis, but catalyzing halocyclization with high enantioselectivity remains a challenging task. Identifying suitable enzymes that catalyze enantioselective halocyclizatio...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Mondal, Dibyendu, Fisher, Brian F., Jiang, Yuhua, Lewis, Jared C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169660/
https://ncbi.nlm.nih.gov/pubmed/34075034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23503-3
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