Site-Selective C–H Halogenation Using Flavin-Dependent Halogenases Identified via Family-Wide Activity Profiling

[Image: see text] Enzymes are powerful catalysts for site-selective C–H bond functionalization. Identifying suitable enzymes for this task and for biocatalysis in general remains challenging, however, due to the fundamental difficulty of predicting catalytic activity from sequence information. In th...

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Detaylı Bibliyografya
Yayımlandı:ACS Cent Sci
Asıl Yazarlar: Fisher, Brian F., Snodgrass, Harrison M., Jones, Krysten A., Andorfer, Mary C., Lewis, Jared C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2019
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6891866/
https://ncbi.nlm.nih.gov/pubmed/31807686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.9b00835
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