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Understanding Flavin-Dependent Halogenase Reactivity via Substrate Activity Profiling
The activity of four native FDHs and four engineered FDH variants on 93 low molecular weight arenes was used to generate FDH substrate activity profiles. These profiles provided insights into how substrate class, functional group substitution, electronic activation, and binding impact FDH activity a...
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| 出版年: | ACS Catal |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5627516/ https://ncbi.nlm.nih.gov/pubmed/28989809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.6b02707 |
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