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Predicting the Substrate Scope of the Flavin‐Dependent Halogenase BrvH

The recently described flavin‐dependent halogenase BrvH is able to catalyse both the bromination and chlorination of indole, but shows significantly higher bromination activity. BrvH was annotated as a tryptophan halogenase, but does not accept tryptophan as a substrate. Its native substrate remains...

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Detalhes bibliográficos
Publicado no:Chembiochem
Main Authors: Neubauer, Pia R., Pienkny, Silke, Wessjohann, Ludger, Brandt, Wolfgang, Sewald, Norbert
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7754283/
https://ncbi.nlm.nih.gov/pubmed/32645255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.202000444
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