A flavin-dependent halogenase from metagenomic analysis prefers bromination over chlorination

Flavin-dependent halogenases catalyse halogenation of aromatic compounds. In most cases, this reaction proceeds with high regioselectivity and requires only the presence of FADH(2), oxygen, and halide salts. Since marine habitats contain high concentrations of halides, organisms populating the ocean...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Neubauer, Pia R., Widmann, Christiane, Wibberg, Daniel, Schröder, Lea, Frese, Marcel, Kottke, Tilman, Kalinowski, Jörn, Niemann, Hartmut H., Sewald, Norbert
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945002/
https://ncbi.nlm.nih.gov/pubmed/29746521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196797
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