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Flavin Adenine Dinucleotide-Dependent Halogenase XanH and Engineering of Multifunctional Fusion Halogenases

Xantholipin (compound 1), a polycyclic xanthone antibiotic, exhibited strong antibacterial activities and showed potent cytotoxicity. The biosynthetic gene cluster of compound 1 has been identified in our previous work, and the construction of xanthone nucleus has been well demonstrated. However, li...

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Pubblicato in:Appl Environ Microbiol
Autori principali: Kong, Lingxin, Wang, Qing, Deng, Zixin, You, Delin
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7480370/
https://ncbi.nlm.nih.gov/pubmed/32651204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01225-20
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