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A flavin-dependent halogenase catalyzes the chlorination step in the biosynthesis of Dictyostelium differentiation-inducing factor 1

Differentiation-inducing factor 1 (DIF-1) is a polyketide-derived morphogen which drives stalk cell formation in the developmental cycle of Dictyostelium discoideum. Previous experiments demonstrated that the biosynthetic pathway proceeds via dichlorination of the precursor molecule THPH, but the en...

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Bibliografiset tiedot
Päätekijät: Neumann, Christopher S., Walsh, Christopher T., Kay, Robert R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851905/
https://ncbi.nlm.nih.gov/pubmed/20231486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001681107
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