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Biosynthesis of (-)-(1S,2R)-allocoronamic acyl thioester by an Fe(II)-dependent halogenase and a cyclopropane-forming flavoprotein

[Image: see text] The biosynthetic gene cluster for the kutzneride family of hexapeptidolactones includes the four-gene cassette ktzABCD postulated to generate a nonproteinogenic amino acid. Encoded by this cassette are the nonheme Fe(II)-dependent halogenase KtzD and the acyl-CoA dehydrogenase-like...

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Detalhes bibliográficos
Main Authors: Neumann, Christopher S., Walsh, Christopher T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650506/
https://ncbi.nlm.nih.gov/pubmed/18828590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja8064667
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