Chemical synthesis of acyl thioesters of acyl carrier protein with native structure.

The acyl carrier protein (ACP) of Escherichia coli was converted to acyl-ACP by imidazole-catalyzed S-acylation with N-acylimidazole. The acylation was specific to the sulfhydryl group; no acylation of tyrosine or amino groups of the protein occurred. The acyl-ACP substrates synthesized had a native...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Cronan, J E, Klages, A L
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1981
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348761/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7029535/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.9.5440
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