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Native N-glycopeptide thioester synthesis through N→S acyl transfer
Peptide thioesters are important tools for the total synthesis of proteins using native chemical ligation (NCL). Preparation of glycopeptide thioesters, that enable the assembly of homogeneously glycosylated proteins, is complicated by the perceived fragile nature of the sugar moiety. Herein, we dem...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Science Ltd
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3160546/ https://ncbi.nlm.nih.gov/pubmed/21676613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.05.059 |
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