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One Atom Matters: Modifying the Thioester Linkage Affects the Structure of the Acyl Carrier Protein
At the center of many complex biosynthetic pathways, the acyl carrier protein (ACP) shuttles substrates to appropriate enzymatic partners to produce fatty acids and polyketides. Carrier proteins covalently tether their cargo by a thioester linkage to a phosphopantetheine cofactor. Due to the labile...
में बचाया:
| में प्रकाशित: | Angew Chem Int Ed Engl |
|---|---|
| मुख्य लेखकों: | , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2019
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6663632/ https://ncbi.nlm.nih.gov/pubmed/31140212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201903815 |
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