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One Atom Matters: Modifying the Thioester Linkage Affects the Structure of the Acyl Carrier Protein
At the center of many complex biosynthetic pathways, the acyl carrier protein (ACP) shuttles substrates to appropriate enzymatic partners to produce fatty acids and polyketides. Carrier proteins covalently tether their cargo by a thioester linkage to a phosphopantetheine cofactor. Due to the labile...
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| 出版年: | Angew Chem Int Ed Engl |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6663632/ https://ncbi.nlm.nih.gov/pubmed/31140212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201903815 |
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