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Glucagon transiently stimulates mTORC1 by activation of an EPAC/Rap1 signaling axis
Activation of the protein kinase mechanistic target of rapamycin (mTOR) in both complexes 1 and 2 (mTORC1/2) in the liver is repressed during fasting and rapidly stimulated in response to a meal. The effect of feeding on hepatic mTORC1/2 is attributed to an increase in plasma levels of nutrients, su...
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| Published in: | Cell Signal |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2021
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8169602/ https://ncbi.nlm.nih.gov/pubmed/33872697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2021.110010 |
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