Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Thousands of interactions assemble proteins into modules that impart spatial and functional organization to the cellular proteome. Through affinity-purification mass spectrometry, we have created two proteome-scale, cell-line-specific interaction networks. The first, BioPlex 3.0, results from affini...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell
Prif Awduron: Huttlin, Edward L., Bruckner, Raphael J., Navarrete-Perea, Jose, Cannon, Joe R., Baltier, Kurt, Gebreab, Fana, Gygi, Melanie P., Thornock, Alexandra, Zarraga, Gabriela, Tam, Stanley, Szpyt, John, Gassaway, Brandon M., Panov, Alexandra, Parzen, Hannah, Fu, Sipei, Golbazi, Arvene, Maenpaa, Eila, Stricker, Keegan, Thakurta, Sanjukta Guha, Zhang, Tian, Rad, Ramin, Pan, Joshua, Nusinow, David P., Paulo, Joao A., Schweppe, Devin K., Vaites, Laura Pontano, Harper, J. Wade, Gygi, Steven P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8165030/
https://ncbi.nlm.nih.gov/pubmed/33961781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2021.04.011
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