Investigation of Proteomic and Phosphoproteomic Responses to Signaling Network Perturbations Reveals Functional Pathway Organizations in Yeast

Governance of protein phosphorylation by kinases and phosphatases constitutes an essential regulatory network in eukaryotic cells. Network dysregulation leads to severe consequences and is often a key factor in disease pathogenesis. Previous studies revealed multiple roles for protein phosphorylatio...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Li, Jiaming, Paulo, Joao A., Nusinow, David P., Huttlin, Edward L., Gygi, Steven P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382779/
https://ncbi.nlm.nih.gov/pubmed/31722220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.10.034
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