Investigation of Proteomic and Phosphoproteomic Responses to Signaling Network Perturbations Reveals Functional Pathway Organizations in Yeast

Governance of protein phosphorylation by kinases and phosphatases constitutes an essential regulatory network in eukaryotic cells. Network dysregulation leads to severe consequences and is often a key factor in disease pathogenesis. Previous studies revealed multiple roles for protein phosphorylatio...

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Vydáno v:Cell Rep
Hlavní autoři: Li, Jiaming, Paulo, Joao A., Nusinow, David P., Huttlin, Edward L., Gygi, Steven P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382779/
https://ncbi.nlm.nih.gov/pubmed/31722220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.10.034
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