Bromodomain and extraterminal (BET) protein inhibition of IgG/IgE production in murine B cells is counter‐balanced by a strong Th2 bias

OBJECTIVES: Inhibitors of bromodomain and extra terminal domain (BET) proteins are a new and growing class of anti‐cancer drugs, which decrease oncogene expression by targeting superenhancers. Antibody production is another physiological process relying on superenhancers, and it remains to be clarif...

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Publicado en:Clin Transl Immunology
Autores principales: Dalloul, Zeinab, Best, Marie, Chenuet, Pauline, Dalloul, Iman, Le Noir, Sandrine, Togbé, Dieudonnée, Gador, Mylène, Ryffel, Bernhard, FJ Quesniaux, Valerie, El Makhour, Yolla, Boyer, François, Aldigier, Jean‐Claude, Cook‐Moreau, Jeanne, Fazilleau, Nicolas, Cogné, Michel
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2021
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8164936/
https://ncbi.nlm.nih.gov/pubmed/34136216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1280
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