Targeting basal-like breast tumors with bromodomain and extraterminal domain (BET) and polo-like kinase inhibitors

Metastatic triple negative breast cancer (TNBC) is an incurable disease with limited therapeutic options, and no targeted therapies available. Triple negative tumors and the basal-like genomic subtype, are both characterized by a high proliferation rate and an increase in cell division. In this cont...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Nieto-Jiménez, Cristina, Alcaraz-Sanabria, Ana, Pérez-Peña, Javier, Corrales-Sánchez, Verónica, Serrano-Heras, Gemma, Galán-Moya, Eva M., Serrano-Oviedo, Leticia, Montero, Juan Carlos, Burgos, Miguel, Llopis, Juan, Pandiella, Atanasio, Ocaña, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386699/
https://ncbi.nlm.nih.gov/pubmed/28061448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14465
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