Comparative structure-function analysis of bromodomain and extraterminal motif (BET) proteins in a gene-complementation system

The widely expressed bromodomain and extraterminal motif (BET) proteins bromodomain-containing protein 2 (BRD2), BRD3, and BRD4 are multifunctional transcriptional regulators that bind acetylated chromatin via their conserved tandem bromodomains. Small molecules that target BET bromodomains are bein...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Werner, Michael T., Wang, Hongxin, Hamagami, Nicole, Hsu, Sarah C., Yano, Jennifer A., Stonestrom, Aaron J., Behera, Vivek, Zong, Yichen, Mackay, Joel P., Blobel, Gerd A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029111/
https://ncbi.nlm.nih.gov/pubmed/31792058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010679
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