Bromodomain and Extraterminal (BET) Protein Inhibition Restores Redox Balance and Inhibits Myofibroblast Activation

BACKGROUND AND OBJECTIVE: Progressive pulmonary fibrosis is the main cause of death in patients with systemic sclerosis (SSc) with interstitial lung disease (ILD) and in those with idiopathic pulmonary fibrosis (IPF). Transforming growth factor-β (TGF-β) and NADPH oxidase- (NOX-) derived reactive ox...

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Detaylı Bibliyografya
Yayımlandı:Biomed Res Int
Asıl Yazarlar: Stock, Carmel J. W., Michaeloudes, Charalambos, Leoni, Patricia, Durham, Andrew L., Mumby, Sharon, Wells, Athol U., Chung, Kian Fan, Adcock, Ian M., Renzoni, Elisabetta A., Lindahl, Gisela E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Hindawi 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500679/
https://ncbi.nlm.nih.gov/pubmed/31119153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/1484736
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