Benchmark Concentrations for Untargeted Metabolomics Versus Transcriptomics for Liver Injury Compounds in In Vitro Liver Models

Interpretation of untargeted metabolomics data from both in vivo and physiologically relevant in vitro model systems continues to be a significant challenge for toxicology research. Potency-based modeling of toxicological responses has served as a pillar of interpretive context and translation of te...

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Bibliografiske detaljer
Udgivet i:Toxicol Sci
Main Authors: Crizer, David M, Ramaiahgari, Sreenivasa C, Ferguson, Stephen S, Rice, Julie R, Dunlap, Paul E, Sipes, Nisha S, Auerbach, Scott S, Merrick, Bruce Alex, DeVito, Michael J
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2021
Fag:
Emerging Technologies, Methods, and Models
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8163038/
https://ncbi.nlm.nih.gov/pubmed/33749773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfab036
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