Benchmark Concentrations for Untargeted Metabolomics Versus Transcriptomics for Liver Injury Compounds in In Vitro Liver Models

Interpretation of untargeted metabolomics data from both in vivo and physiologically relevant in vitro model systems continues to be a significant challenge for toxicology research. Potency-based modeling of toxicological responses has served as a pillar of interpretive context and translation of te...

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Опубликовано в: :Toxicol Sci
Главные авторы: Crizer, David M, Ramaiahgari, Sreenivasa C, Ferguson, Stephen S, Rice, Julie R, Dunlap, Paul E, Sipes, Nisha S, Auerbach, Scott S, Merrick, Bruce Alex, DeVito, Michael J
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2021
Предметы:
Emerging Technologies, Methods, and Models
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8163038/
https://ncbi.nlm.nih.gov/pubmed/33749773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfab036
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