Benchmark Concentrations for Untargeted Metabolomics Versus Transcriptomics for Liver Injury Compounds in In Vitro Liver Models

Interpretation of untargeted metabolomics data from both in vivo and physiologically relevant in vitro model systems continues to be a significant challenge for toxicology research. Potency-based modeling of toxicological responses has served as a pillar of interpretive context and translation of te...

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Vydáno v:Toxicol Sci
Hlavní autoři: Crizer, David M, Ramaiahgari, Sreenivasa C, Ferguson, Stephen S, Rice, Julie R, Dunlap, Paul E, Sipes, Nisha S, Auerbach, Scott S, Merrick, Bruce Alex, DeVito, Michael J
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2021
Témata:
Emerging Technologies, Methods, and Models
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8163038/
https://ncbi.nlm.nih.gov/pubmed/33749773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfab036
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