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From the Cover: Three-Dimensional (3D) HepaRG Spheroid Model With Physiologically Relevant Xenobiotic Metabolism Competence and Hepatocyte Functionality for Liver Toxicity Screening

Effective prediction of human responses to chemical and drug exposure is of critical importance in environmental toxicology research and drug development. While significant progress has been made to address this challenge using invitro liver models, these approaches often fail due to inadequate tiss...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Ramaiahgari, Sreenivasa C., Waidyanatha, Suramya, Dixon, Darlene, DeVito, Michael J., Paules, Richard S., Ferguson, Stephen S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837526/
https://ncbi.nlm.nih.gov/pubmed/28633424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfx122
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