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From the Cover: Three-Dimensional (3D) HepaRG Spheroid Model With Physiologically Relevant Xenobiotic Metabolism Competence and Hepatocyte Functionality for Liver Toxicity Screening

Effective prediction of human responses to chemical and drug exposure is of critical importance in environmental toxicology research and drug development. While significant progress has been made to address this challenge using invitro liver models, these approaches often fail due to inadequate tiss...

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Dettagli Bibliografici
Pubblicato in:Toxicol Sci
Autori principali: Ramaiahgari, Sreenivasa C., Waidyanatha, Suramya, Dixon, Darlene, DeVito, Michael J., Paules, Richard S., Ferguson, Stephen S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837526/
https://ncbi.nlm.nih.gov/pubmed/28633424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfx122
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