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LRR1-mediated replisome disassembly promotes DNA replication by recycling replisome components
After two converging DNA replication forks meet, active replisomes are disassembled and unloaded from chromatin. A key process in replisome disassembly is the unloading of CMG helicases (CDC45–MCM–GINS), which is initiated in Caenorhabditis elegans and Xenopus laevis by the E3 ubiquitin ligase CRL2(...
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| Publicat a: | J Cell Biol |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Rockefeller University Press
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8160578/ https://ncbi.nlm.nih.gov/pubmed/34037657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202009147 |
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