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CRL2(Lrr1) promotes unloading of the vertebrate replisome from chromatin during replication termination
A key event during eukaryotic replication termination is the removal of the CMG helicase from chromatin. CMG unloading involves ubiquitylation of its Mcm7 subunit and the action of the p97 ATPase. Using a proteomic screen in Xenopus egg extracts, we identified factors that are enriched on chromatin...
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| Publicat a: | Genes Dev |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5358724/ https://ncbi.nlm.nih.gov/pubmed/28235849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.291799.116 |
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