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TRAIP drives replisome disassembly and mitotic DNA repair synthesis at sites of incomplete DNA replication
The faithful segregation of eukaryotic chromosomes in mitosis requires that the genome be duplicated completely prior to anaphase. However, cells with large genomes sometimes fail to complete replication during interphase and instead enter mitosis with regions of incompletely replicated DNA. These r...
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| Опубликовано в: : | eLife |
|---|---|
| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
eLife Sciences Publications, Ltd
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6773462/ https://ncbi.nlm.nih.gov/pubmed/31545170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.48686 |
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