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TRAIP drives replisome disassembly and mitotic DNA repair synthesis at sites of incomplete DNA replication

The faithful segregation of eukaryotic chromosomes in mitosis requires that the genome be duplicated completely prior to anaphase. However, cells with large genomes sometimes fail to complete replication during interphase and instead enter mitosis with regions of incompletely replicated DNA. These r...

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Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Sonneville, Remi, Bhowmick, Rahul, Hoffmann, Saskia, Mailand, Niels, Hickson, Ian D, Labib, Karim
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773462/
https://ncbi.nlm.nih.gov/pubmed/31545170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.48686
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